3-(Benzothiazole-2-yl)-4-fluoroaniline

Base Information

Chemical Name:3-(Benzothiazole-2-yl)-4-fluoroaniline
CAS No.:220705-29-3
Molecular Formula:C₁₃H₉FN₂S
Molecular Weight:244.292
Hs Code.:
DSSTox Substance ID:DTXSID201277111
Nikkaji Number:J1.047.973H

Synonyms:DTXSID201277111;AKOS005917262;3-(Benzothiazole-2-yl)-4-fluoroaniline;220705-29-3;3-(2-Benzothiazolyl)-4-fluorobenzenamine

Suppliers and Price of 3-(Benzothiazole-2-yl)-4-fluoroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 3-(Benzothiazole-2-yl)-4-fluoroaniline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:244.04704763
Heavy Atom Count:17
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=C(S2)C3=C(C=CC(=C3)N)F

Technology Process of 3-(Benzothiazole-2-yl)-4-fluoroaniline

There total 3 articles about 3-(Benzothiazole-2-yl)-4-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 56741-33-4
5-amino-2-fluorobenzoic acid

: 137-07-5
2-amino-benzenethiol

: 220705-29-3
3-benzothiazol-2-yl-4-fluorophenylamine

Guidance literature:: With PPA; at 210 ℃; for 4h;
DOI:10.1002/jhet.5570350610

Reference yield:

: 7304-32-7
2-fluoro-5-nitrobenzoic acid

: 220705-29-3
3-benzothiazol-2-yl-4-fluorophenylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / cyclohexene / 10 percent Pd/C / ethanol / 6 h / Heating

2: 87 percent / PPA / 4 h / 210 °C

With cyclohexene; palladium on activated charcoal; In ethanol;
DOI:10.1002/jhet.5570350610

Reference yield:

: 445-29-4
o-fluoro-benzoic acid

: 220705-29-3
3-benzothiazol-2-yl-4-fluorophenylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 88 percent / fuming HNO₃, conc. H₂SO₄ / 0.75 h / 80 - 90 °C

2: 89 percent / cyclohexene / 10 percent Pd/C / ethanol / 6 h / Heating

3: 87 percent / PPA / 4 h / 210 °C

With sulfuric acid; nitric acid; cyclohexene; palladium on activated charcoal; In ethanol;
DOI:10.1002/jhet.5570350610