1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

Base Information

Chemical Name:1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide
CAS No.:1309081-42-2
Molecular Formula:C₁₇H₁₈N₂O₄
Molecular Weight:314.341
Hs Code.:

Synonyms:1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

Chemical Property:

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Technology Process of 1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

There total 1 articles about 1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1174207-59-0
1-formyl-4-oxo-4H-quinolizine-3-carboxylic acid

: 931-15-7,931-16-8,6850-38-0,6982-39-4,33092-82-9,38898-70-3,74111-21-0,108267-20-5
(1S,2S)-trans-2-aminocyclohexanol

: 1309081-42-2
1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; for 0.5h; Inert atmosphere;
DOI:10.1021/ml300280g

Reference yield: 79.0%

: 1309081-42-2
1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

: 82117-35-9
3-(piperazin-1-yl)-isoquinoline

: 1309079-99-9
C₃₀H₃₃N₅O₃

Guidance literature:: With acetic acid; In 1,2-dichloro-ethane; at 120 ℃; for 0.333333h; MP-cyanoborohydride resin? Microwave irradiation;
DOI:10.1021/ml300280g

Reference yield:

: 1309081-42-2
1-formyl-N-((1S,2S)-2-hydroxycyclohexyl)-4-oxo-4H-quinolizine-3-carboxamide

: 767263-33-2
4-(pyridine-2-yl)piperidine-4-carbonitrile

: 1309080-22-5
C₂₉H₃₂N₄O₃

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1021/ml300280g