2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide

Base Information

• Chemical Name: 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide
• CAS No.: 439863-90-8
• Molecular Formula: C₁₄H₁₉N₃OS
• Molecular Weight: 277.39

Synonyms:2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide

Chemical Property of 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide

There total 1 articles about 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-diaminobutane (110-60-1) + 2-anilino-2-methoxy-3-oxothiobutanoic acid anilide → 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide (439863-90-8)

Guidance literature:

In toluene; at 75 ℃; for 0.0833333h;

DOI:10.1055/s-2002-34866

Reference yield: 70.0%

thiophosgene (463-71-8) + 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide (439863-90-8) → 2,3,4,5,7,9-hexahydro-9-methyl-9-(N-phenylthio-carbamoyl)-[1,3]oxazolo[3,4-a][1,3]diazepin-7-thione

Guidance literature:

With sodium hydrogencarbonate; In chloroform; at 0 ℃; for 0.666667h;

DOI:10.1055/s-2002-34866

Reference yield: 65.0%

C14H19N3OS (439863-90-8) + dimethyl acetylenedicarboxylate (762-42-5) → 10-methyl-13-oxa-2-oxo-12-phenyl-11-thioxo-3,8,12-triazatricyclo[8.2.1.0(3,9)]tridec-8-en-1-ylacetic acid methyl ester (1233927-73-5)

Guidance literature:

In methanol; for 0.666667h; Reflux;

DOI:10.1055/s-0029-1218710

upstream raw materials:

1,4-diaminobutane

Downstream raw materials:

bis(diphenyl)urea

1,3-Dicyclohexylurea

1,3-dinaphthalen-1-ylurea

10-methyl-13-oxa-2-oxo-12-phenyl-11-thioxo-3,8,12-triazatricyclo[8.2.1.0(3,9)]tridec-8-en-1-ylacetic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 439863-90-8 2-hydroxy-N-phenyl-2-(4,5,6,7-tetrahydro-1H-[1,3]diazepin-2-yl)-thiopropionamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send