2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Base Information

Chemical Name:2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile
CAS No.:264272-46-0
Molecular Formula:C₁₉H₂₃N₃O
Molecular Weight:309.411
Hs Code.:

Synonyms:2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Suppliers and Price of 2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(1,1-Dimethylethyl)-α-[hydroxy(1,3,4-trimethyl-1H-pyrazol-5-yl)methylene]benzeneacetonitrile(E/Zmixture)
100mg
$ 1240.00

TRC
4-(1,1-Dimethylethyl)-α-[hydroxy(1,3,4-trimethyl-1H-pyrazol-5-yl)methylene]benzeneacetonitrile(E/Zmixture)
50mg
$ 690.00

TRC
4-(1,1-Dimethylethyl)-α-[hydroxy(1,3,4-trimethyl-1H-pyrazol-5-yl)methylene]benzeneacetonitrile(E/Zmixture)
10mg
$ 150.00

Total 0 raw suppliers

Chemical Property of 2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Chemical Property:

Melting Point:>70°C (dec.)
Boiling Point:446.9±45.0 °C(Predicted)
Density:1.06±0.1 g/cm3(Predicted)

Purity/Quality:: 4-(1,1-Dimethylethyl)-α-[hydroxy(1,3,4-trimethyl-1H-pyrazol-5-yl)methylene]benzeneacetonitrile(E/Zmixture) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-(1,1-Dimethylethyl)-α-[hydroxy(1,3,4-trimethyl-1H-pyrazol-5-yl)methylene]benzeneacetonitrile is an intermediate used in the preparation of Cyenopyrafen, a potent acaricide.

Technology Process of 2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

There total 10 articles about 2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 773136-70-2
methyl 1,3,4-trimethylpyrazole-5-carboxylate

: 3288-99-1
4-tert-butylbenzyl cyanide

: 264272-46-0
2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Guidance literature:: methyl 1,3,4-trimethylpyrazole-5-carboxylate; 4-tert-butylbenzyl cyanide; With 2-ethoxy-ethanol; In n-heptane; at 20 - 95 ℃; for 1h; Inert atmosphere;

With sodium methylate; In methanol; n-heptane; for 5h; Inert atmosphere;
DOI:10.3998/ark.5550190.0013.603

Reference yield:

: 5744-40-1
ethyl 1,3-dimethylpyrazole-5-carboxylate

: 264272-46-0
2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: sulfuric acid; hydrogenchloride / 1,4-dioxane; water / 5 h / Reflux

2.1: 5%-palladium/activated carbon; hydrogen / ethanol; water / 6 h / 20 °C

3.1: 2-methoxy-ethanol; n-heptane / 1 h / Reflux

3.2: 5 h / Reflux

With hydrogenchloride; sulfuric acid; 5%-palladium/activated carbon; hydrogen; In 1,4-dioxane; ethanol; n-heptane; 2-methoxy-ethanol; water;
DOI:10.1002/jhet.2682

Reference yield:

: 166313-45-7
1,3-dimethyl-4-chloromethylpyrazole-5-carboxylic acid ethyl ester

: 264272-46-0
2-(4-tert-butylphenyl)-3-hydroxy-3-(1,3,4-trimethyl-1H-pyrazol-5-yl)acrylonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: 5%-palladium/activated carbon; hydrogen / ethanol; water / 6 h / 20 °C

2.1: 2-methoxy-ethanol; n-heptane / 1 h / Reflux

2.2: 5 h / Reflux

With 5%-palladium/activated carbon; hydrogen; In ethanol; n-heptane; 2-methoxy-ethanol; water;
DOI:10.1002/jhet.2682