1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Base Information

Chemical Name:1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol
CAS No.:946827-26-5
Molecular Formula:C₆₃H₉₄N₂O₈Si
Molecular Weight:1035.53
Hs Code.:

Synonyms:1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

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Chemical Property of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

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Technology Process of 1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

There total 1 articles about 1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 946827-19-6
1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

: 57-88-5
cholesterol

: 530-62-1
1,1'-carbonyldiimidazole

: 946827-26-5
1-O-(4,4'-dimethoxytrityl)-2-O-[N-cholesteryloxycarbonyl-N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol

Guidance literature:: cholesterol; 1,1'-carbonyldiimidazole; With pyridine; In dichloromethane; at 20 ℃; for 2h;

1-O-(4,4'-dimethoxytrityl)-2-O-[N-(4-aminobutyl)carbamoyl]-3-O-tert-butyldimethylsilylglycerol; at 20 ℃; for 12h;
DOI:10.1016/j.bmc.2008.07.010