10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride

Base Information

Chemical Name:10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride
CAS No.:3763-80-2
Molecular Formula:C15H15ClN2S
Molecular Weight:327.277
Hs Code.:
NSC Number:168977
UNII:FE9NJ19KHJ
DSSTox Substance ID:DTXSID40191067
ChEMBL ID:CHEMBL1991732
Mol file:3763-80-2.mol

Synonyms:3763-80-2;SKF 4577A;NSC 168977;FE9NJ19KHJ;10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride;3-(2-chlorophenothiazin-10-yl)propan-1-amine hydrochloride;Didemethylchlorpromazine hydrochloride;NSC-168977;3-(2-Chloro-10-phenothiazinyl)propylamine hydrochloride;3-(2-chlorophenothiazin-10-yl)propan-1-amine;hydrochloride;Propylamine, 3-(2-chloro-10-phenothiazinyl)-, hydrochloride;NSC168977;Didesmethylchlorpromazine Hydrochloride;UNII-FE9NJ19KHJ;C15H15ClN2S.ClH;CHEMBL1991732;SCHEMBL14697764;DTXSID40191067;C15-H15-Cl-N2-S.Cl-H;C(CCN)N1c2ccccc2Sc3ccc(Cl)cc13;LS-125575;10H-Phenothiazine-10-propanamine, monohydrochloride;2-chloro-10-(3-aminopropyl)phenothiazine hydrochloride;3-(2-chloro-10H-phenothiazin-10-yl)-1-propanamine hydrochloride;3-(2-chloro-10H-phenothiazin-10-yl)propan-1-amine hydrochloride;10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride (9CI)

Suppliers and Price of 10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride

Chemical Property:

Vapor Pressure:1.61E-08mmHg at 25°C
Boiling Point:456.5°C at 760 mmHg
Flash Point:229.9°C
Density:1.284g/cm³
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:326.0411251
Heavy Atom Count:20
Complexity:302

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N(C3=C(S2)C=CC(=C3)Cl)CCCN.Cl

Technology Process of 10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride

There total 2 articles about 10H-Phenothiazine-10-propanamine, 2-chloro-, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 180388-71-0
N-[3-(2-chloro-phenothiazin-10-yl)-propyl]-phthalimide

: 3763-80-2
3-(2-chloro-10H-phenothiazin-10-yl)propan-1-amine hydrochloride

Guidance literature:: With hydrogenchloride; hydrazine; In 1,4-dioxane; ethanol;
DOI:10.1016/j.bmc.2015.07.007

Reference yield:

: 92-39-7
2-chlorophenothiazine

: 3763-80-2
3-(2-chloro-10H-phenothiazin-10-yl)propan-1-amine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide; mineral oil

2: hydrogenchloride; hydrazine / ethanol; 1,4-dioxane

With hydrogenchloride; sodium hydride; hydrazine; In 1,4-dioxane; ethanol; N,N-dimethyl-formamide; mineral oil;
DOI:10.1016/j.bmc.2015.07.007