(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Base Information

Chemical Name:(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride
CAS No.:1404054-64-3
Molecular Formula:C₂₇H₂₇Cl₂N₂O₃S*Cl
Molecular Weight:565.948
Hs Code.:

Synonyms:(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Suppliers and Price of (3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

There total 3 articles about (3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29683-77-0
2-chloro-1-(thiophen-2-yl)ethanone

: 1404054-63-2
(2-chlorophenyl)(4-chlorophenyl)methyl (R)-quinuclidin-3-ylcarbamate

: 1404054-64-3
(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Guidance literature:: In ethyl acetate; acetonitrile; at 20 ℃;

Reference yield:

: 6530-09-2,119904-90-4,120538-52-5,123536-14-1,124577-62-4,126358-22-3,137661-30-4,137661-31-5
(3R)-quinuclidin-3-amine dihydrochloride

: 1404054-64-3
(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydrogencarbonate / water; methanol / 1 h / 20 °C

1.2: 7 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.33 h / 0 - 20 °C

2.2: 20 °C

3.1: ethyl acetate; acetonitrile / 20 °C

With sodium hydride; sodium hydrogencarbonate; In methanol; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; mineral oil;

Reference yield:

: 43171-49-9
(2-chlorophenyl)(4'-chlorophenyl)methanol

: 6530-09-2,119904-90-4,120538-52-5,123536-14-1,124577-62-4,126358-22-3,137661-30-4,137661-31-5
(3R)-quinuclidin-3-amine dihydrochloride

: 1404054-64-3
(3R)-3-(((2-chlorophenyl)(4-chlorophenyl)methoxy)-carbonylamino)-1-(2-oxo-2-(thiophen-2-yl)ethyl)-1-azoniabicyclo-[2.2.2]octane chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / water; methanol / 1 h / 20 °C

1.2: 20 °C

1.3: 20 °C

2.1: ethyl acetate / 20 °C

With sodium hydrogencarbonate; In methanol; water; ethyl acetate;