trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

Base Information

Chemical Name:trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride
CAS No.:103305-05-1
Molecular Formula:C₃₉H₅₀N₆O₆*ClH
Molecular Weight:735.324
Hs Code.:

Synonyms:trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

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Technology Process of trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

There total 2 articles about trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 81638-87-1
hydrochloride of amide of glycylglycyl-L-phenylalanyl-L-leucine

: trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolic acid hydrochloride

: 103305-05-1
trans-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 24h;
DOI:10.1021/jm00160a039

Reference yield: 55.0%

: 81638-87-1
hydrochloride of amide of glycylglycyl-L-phenylalanyl-L-leucine

: cis-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolic acid hydrochloride

: 103305-05-1
cis-N-benzyl-4-(3-hydroxyphenyl)-4-methylpipecolylglycylglycylphenylalanylleucinamide hydrochloride

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 48h;
DOI:10.1021/jm00160a039