2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate

Base Information

• Chemical Name: 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate
• CAS No.: 913253-38-0
• Molecular Formula: C₂₁H₂₈O₄SSi
• Molecular Weight: 404.602
• Mol file: 913253-38-0.mol

Synonyms:2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate

Chemical Property of 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate

There total 2 articles about 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanesulfonyl chloride (124-63-0) + 2-<(tert-butyldiphenylsilyloxy)methyl>prop-2-en-1-ol (177606-51-8) → 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate (913253-38-0)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 2.25h;

DOI:10.1002/ejoc.200600414

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → 2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate (913253-38-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / NaH / tetrahydrofuran / 0 °C

2: NEt₃ / CH₂Cl₂ / -5 °C

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tetlet.2006.09.104

Reference yield: 95.0%

2-(((tert-butyldiphenylsilyl)oxy)methyl)allyl methanesulfonate (913253-38-0) → {[2-(bromomethyl)prop-2-en-1-yl]oxy}(tert-butyl)diphenylsilane (913253-34-6)

Guidance literature:

With lithium bromide; In diethyl ether; at 20 ℃; for 22h;

DOI:10.1002/ejoc.200600414

upstream raw materials:

methanesulfonyl chloride

2-<(tert-butyldiphenylsilyloxy)methyl>prop-2-en-1-ol

tert-butylchlorodiphenylsilane

Downstream raw materials:

{[2-(bromomethyl)prop-2-en-1-yl]oxy}(tert-butyl)diphenylsilane

tert-butyl-(2-chloromethyl-allyloxy)-diphenyl-silane

C₂₃H₃₄OSi₂

5-(tert-butyl-diphenyl-silanyloxymethyl)-3-methyl-hex-5-enal