C₂₇H₃₆N₂O₅

Base Information

• Chemical Name: C₂₇H₃₆N₂O₅
• CAS No.: 1055233-62-9
• Molecular Formula: C₂₇H₃₆N₂O₅
• Molecular Weight: 468.593
• Mol file: 1055233-62-9.mol

Synonyms:C₂₇H₃₆N₂O₅

Chemical Property of C₂₇H₃₆N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₇H₃₆N₂O₅

There total 8 articles about C₂₇H₃₆N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H33IN2O3 (1055233-61-8) + acrylic acid (79-10-7) → C27H36N2O5 (1055233-62-9)

Guidance literature:

With triethylamine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris-(o-tolyl)phosphine; In N,N-dimethyl-formamide; at 120 ℃; for 10h; Inert atmosphere;

Reference yield:

5-nitro-2-i-propylphenol (170230-13-4) → C27H36N2O5 (1055233-62-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h

2.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C

3.1: toluene-4-sulfonic acid / 1,4-dioxane / 22 h / 100 °C / Reflux

3.2: Saturated solution

4.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere

4.2: 0.17 h / 20 °C

5.1: Iodine monochloride; calcium carbonate / methanol; water / 20 °C

6.1: triethylamine / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 10 h / 120 °C / Inert atmosphere

With hydrogenchloride; hydrogen; Iodine monochloride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; calcium carbonate; potassium iodide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium on activated charcoal; tris-(o-tolyl)phosphine; In 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;

Reference yield:

2-isopropyl-5-nitroaniline (132475-93-5) → C27H36N2O5 (1055233-62-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sulfuric acid; water; sodium nitrite / 0 - 5 °C

2.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h

3.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C

4.1: toluene-4-sulfonic acid / 1,4-dioxane / 22 h / 100 °C / Reflux

4.2: Saturated solution

5.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / 20 °C / Inert atmosphere

5.2: 0.17 h / 20 °C

6.1: Iodine monochloride; calcium carbonate / methanol; water / 20 °C

7.1: triethylamine / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 10 h / 120 °C / Inert atmosphere

With hydrogenchloride; sulfuric acid; water; hydrogen; Iodine monochloride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; calcium carbonate; potassium iodide; sodium nitrite; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium on activated charcoal; tris-(o-tolyl)phosphine; In 1,4-dioxane; methanol; water; N,N-dimethyl-formamide;

upstream raw materials:

C₂₄H₃₃IN₂O₃

acrylic acid

5-nitro-2-i-propylphenol

2-isopropyl-5-nitroaniline

Downstream raw materials:

C₂₃H₂₈N₂O₅

Refernces