3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Base Information

Chemical Name:3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride
CAS No.:1381871-17-5
Molecular Formula:C₄₁H₄₃ClO₈S
Molecular Weight:731.307
Hs Code.:

Synonyms:3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Suppliers and Price of 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

There total 2 articles about 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1381871-16-4
3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranose

: 1381871-17-5
3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Guidance literature:: With pyridine; thionyl chloride; In dichloromethane; at 20 ℃; for 0.333333h; Inert atmosphere;
DOI:10.1016/j.tet.2012.04.067

Reference yield:

: 2,3,6-tri-O-benzyl-4-O-((2-naphthyl)methyl)-α,β-D-glucopyranose

: 1381871-17-5
3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

2.1: n-butyllithium; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 0.25 h / -60 °C / Inert atmosphere

2.2: 3 h / -78 - -60 °C / Inert atmosphere

2.3: Inert atmosphere

3.1: pyridine; thionyl chloride / dichloromethane / 0.33 h / 20 °C / Inert atmosphere

With pyridine; n-butyllithium; thionyl chloride; Dess-Martin periodane; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; 1.1: Dess-Martin oxidation;
DOI:10.1016/j.tet.2012.04.067

Reference yield:

: 1381871-28-8
methyl 3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

: 1381871-17-5
3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl chloride

: 1381871-29-9
methyl 3,4,7-tri-O-benzyl-5-O-((2-naphthyl)methyl)-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranosyl-(2->5)-3,4,7-tri-O-benzyl-1-deoxy-1-ethoxysulfonyl-α-D-gluco-hept-2-ulopyranoside

Guidance literature:: With silver trifluoromethanesulfonate; In dichloromethane; toluene; at 0 ℃; for 120h; Inert atmosphere; Molecular sieve;
DOI:10.1016/j.tet.2012.04.067