1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Base Information

Chemical Name:1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside
CAS No.:81726-70-7
Molecular Formula:C₃₆H₄₆O₇Si
Molecular Weight:618.843
Hs Code.:

Synonyms:1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Suppliers and Price of 1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

There total 7 articles about 1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 81713-19-1
1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-α-D-galactopyranoside

: 81726-70-7
1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Guidance literature:: With dmap; triethylamine; In dichloromethane; N,N-dimethyl-formamide; for 20h;
DOI:10.1016/S0008-6215(00)88053-2

Reference yield:

: 20746-64-9
allyl 4,6-O-benzylidene-α-D-galactopyranoside

: 81726-70-7
1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Guidance literature:: Multi-step reaction with 6 steps

1: 89 percent / sodium hydride / dimethylformamide / 0.5 h / Ambient temperature

2: hydrochloric acid / methanol

3: 90 percent / sodium hydride / dimethylformamide / 0.5 h / Ambient temperature

4: 80 percent / potassium tert-butoxide / dimethylformamide / 2 h / 85 °C

5: 68 percent / pyridine / 10 min -35 deg C, 1 h -30 deg C

6: 90 percent / triethylamine, 4-dimethylaminopyridine / dimethylformamide; CH₂Cl₂ / 20 h

With pyridine; hydrogenchloride; dmap; potassium tert-butylate; sodium hydride; triethylamine; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(00)88053-2

Reference yield:

: 98-88-4
benzoyl chloride

: 81726-70-7
1-propenyl 2-O-benzoyl-4,6-di-O-benzyl-3-O-tert-butyldimethylsilyl-α-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / pyridine / 10 min -35 deg C, 1 h -30 deg C

2: 90 percent / triethylamine, 4-dimethylaminopyridine / dimethylformamide; CH₂Cl₂ / 20 h

With pyridine; dmap; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(00)88053-2