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Nordazepam

Base Information Edit
  • Chemical Name:Nordazepam
  • CAS No.:1088-11-5
  • Molecular Formula:C15H11ClN2O
  • Molecular Weight:270.718
  • Hs Code.:2933910000
  • European Community (EC) Number:214-123-4
  • NSC Number:631619,46078
  • UNII:67220MCM01
  • DSSTox Substance ID:DTXSID2049000
  • Nikkaji Number:J7.250H
  • Wikipedia:Nordazepam
  • Wikidata:Q3180288
  • NCI Thesaurus Code:C87675
  • Metabolomics Workbench ID:52721
  • ChEMBL ID:CHEMBL523
  • Mol file:1088-11-5.mol
Nordazepam

Synonyms:Calmday;Dealkylprazepam;Demethyldiazepam;Deoxydemoxepam;Desmethyldiazepam;N Desalkylhalazepam;N Descyclopropylmethyl Prazepam;N Descyclopropylmethylprazepam;N Destrifluoroethylhalazepam;N-Desalkylhalazepam;N-Descyclopropylmethyl-Prazepam;N-Descyclopropylmethylprazepam;N-Destrifluoroethylhalazepam;Nordaz;Nordazepam;Nordiazepam;Norprazepam;Ro 5 2180;Ro 5-2180;Ro 52180;Tranxilium N;Vegesan

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Nordazepam Edit
Chemical Property:
  • Appearance/Colour:Off-white solid 
  • Vapor Pressure:2.12E-08mmHg at 25°C 
  • Melting Point:208-210°C 
  • Refractive Index:1.66 
  • Boiling Point:453.103 °C at 760 mmHg 
  • PKA:pKa 3.5 12.0 (5%MeOH in H2O t=20 I=0.15) (Uncertain) 
  • Flash Point:227.829 °C 
  • PSA:41.46000 
  • Density:1.323 g/cm3 
  • LogP:2.70310 
  • Storage Temp.:2-8°C 
  • Solubility.:DMSO: >10mg/mL 
  • XLogP3:2.9
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:1
  • Exact Mass:270.0559907
  • Heavy Atom Count:19
  • Complexity:376
Purity/Quality:
Safty Information:
  • Pictogram(s): HarmfulXn,ToxicT,Flammable
  • Hazard Codes:Xn,T,F 
  • Statements: 22-39/23/24/25-23/24/25-11 
  • Safety Statements: 7-16-36/37-45 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1C(=O)NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3
  • Uses The primary metabolite of diazepam. A ligand for the GABAA receptor benzodiazepine modulatory site. This is a controlled drug precursor therefore a liscence may be required for purchase The primary metabolite of Diazepam. A ligand for the GABAA receptor benzodiazepine modulatory site. Anxiolytic. Controlled substance (depressant).
  • Therapeutic Function Tranquilizer
Technology Process of Nordazepam

There total 30 articles about Nordazepam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With ammonium hydroxide; In ethanol; Heating;
DOI:10.1002/jhet.5570180523
Guidance literature:
With ammonium hydroxide; In ethanol; Heating;
DOI:10.1002/jhet.5570180523
Guidance literature:
With ammonium acetate; potassium carbonate; In neat (no solvent); at 20 ℃; for 3h;
DOI:10.1007/s00044-016-1585-z