4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine

Base Information

• Chemical Name: 4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine
• CAS No.: 173279-42-0
• Molecular Formula: C₁₁H₁₁ClFN₅
• Molecular Weight: 267.693
• Mol file: 173279-42-0.mol

Synonyms:4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine

Chemical Property of 4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine

There total 1 articles about 4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

(3,5-dichloropyridazin-4-yl)amine (53180-76-0) + (2-fluorobenzyl)hydrazine (51859-98-4) → 4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine (173279-42-0)

Guidance literature:

at 100 ℃; for 13h;

DOI:10.1002/jhet.5570320503

Reference yield: 87.0%

4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine (173279-42-0) → 4-amino-5-chloro-3-<(2-fluorobenzyl)amino>pyridazine (173279-43-1)

Guidance literature:

With hydrogen; nickel; In ethanol; for 3h; under 2068.6 Torr; Ambient temperature;

DOI:10.1002/jhet.5570320503

Reference yield:

4-amino-5-chloro-3-<1-(2-fluorobenzyl)hydrazino>pyridazine (173279-42-0) → 7-chloro-3-(2-fluorobenzyl)-3H-imidazo<4,5-c>pyridazine (173279-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 87 percent / H₂ / Raney Ni / ethanol / 3 h / 2068.6 Torr / Ambient temperature

2: 62 percent / ethanesulfonic acid / 4 h / 75 - 100 °C

With ethanesulfonic acid; hydrogen; nickel; In ethanol;

DOI:10.1002/jhet.5570320503

upstream raw materials:

(3,5-dichloropyridazin-4-yl)amine

(2-fluorobenzyl)hydrazine

Downstream raw materials:

4-amino-5-chloro-3-<(2-fluorobenzyl)amino>pyridazine

7-chloro-3-(2-fluorobenzyl)-3H-imidazo<4,5-c>pyridazine