(Z)-dimethyl 2-(phenylacetamido)fumarate

Base Information

Chemical Name:(Z)-dimethyl 2-(phenylacetamido)fumarate
CAS No.:1311426-19-3
Molecular Formula:C₁₄H₁₅NO₅
Molecular Weight:277.277
Hs Code.:

Synonyms:(Z)-dimethyl 2-(phenylacetamido)fumarate

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Chemical Property of (Z)-dimethyl 2-(phenylacetamido)fumarate

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Technology Process of (Z)-dimethyl 2-(phenylacetamido)fumarate

There total 1 articles about (Z)-dimethyl 2-(phenylacetamido)fumarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 23025-55-0
N-(ethoxycarbonylimino)pyridinium ylide

: 103-80-0
phenylacetyl chloride

: 624-49-7
dimethylfumarate

: 1311426-19-3
(Z)-dimethyl 2-(phenylacetamido)fumarate

Guidance literature:: N-(ethoxycarbonylimino)pyridinium ylide; dimethylfumarate; With silicic acid; In 5,5-dimethyl-1,3-cyclohexadiene; at 130 ℃; for 48h;

phenylacetyl chloride; With pyridine; In dichloromethane; at 20 ℃; for 48h;
DOI:10.1002/adsc.201100042

Reference yield:

: 1311426-19-3
(Z)-dimethyl 2-(phenylacetamido)fumarate

: C₁₄H₁₆⁽²⁾HNO₅

Guidance literature:: With D-glucose; Old Yellow Enzyme-3; water-d2; NADH; In aq. phosphate buffer; isopropyl alcohol; at 30 ℃; for 24h; pH=7; enantioselective reaction; Enzymatic reaction;
DOI:10.1016/j.molcatb.2013.12.020

Reference yield:

: 1311426-19-3
(Z)-dimethyl 2-(phenylacetamido)fumarate

: 162815-64-7
rac-dimethyl 2-(phenylacetamido)succinate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃; under 760.051 Torr;
DOI:10.1002/adsc.201100042