N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE

Base Information

Chemical Name:N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE
CAS No.:329281-02-9
Molecular Formula:C₁₄H₁₄BrNO₃S
Molecular Weight:356.24
Hs Code.:
Mol file:329281-02-9.mol

Synonyms:N-(4-bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide

Suppliers and Price of N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(4-Bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide 97%
1g
$ 643.00

Total 1 raw suppliers

Chemical Property of N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE

Chemical Property:

Purity/Quality:: N-(4-Bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE

There total 6 articles about N-(4-BROMO-2-HYDROXYMETHYL-PHENYL)-4-METHYL-BENZENESULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 98-59-9
p-toluenesulfonyl chloride

: 20712-12-3
(2-amino-5-bromophenyl)methanol

: 329281-02-9
N-(4-bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/acs.orglett.9b01580

Reference yield:

: 5794-88-7
5-Bromo-2-aminobenzoic acid

: 329281-02-9
N-(4-bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: pyridine / dichloromethane / 12 h / 0 °C / Inert atmosphere; Reflux

With pyridine; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/cs4000014

Reference yield:

: 1241894-37-0
5-bromo-2-nitrobenzylic alcohol

: 329281-02-9
N-(4-bromo-2-(hydroxymethyl)phenyl)-4-methylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: iron; ammonium chloride / methanol; water / 8 h / 80 °C / Inert atmosphere

2: pyridine / dichloromethane / 3 h / 25 °C / Inert atmosphere

With pyridine; iron; ammonium chloride; In methanol; dichloromethane; water;
DOI:10.1021/acs.orglett.9b01295