20712-12-3

Basic information

• Product Name: (2-AMINO-5-BROMOPHENYL)METHANOL
• Synonyms: (2-AMINO-5-BROMOPHENYL)METHANOL;(2-AMINO-5-BROMOPHENYL)METHANOL（WS200466）
• CAS NO: 20712-12-3
• Molecular Formula: C₇H₈BrNO
• Molecular Weight: 202.05
• Mol File: 20712-12-3.mol
• Article Data: 57

Chemical Properties

• Boiling Point: 329.556 °C at 760 mmHg
• Flash Point: 153.11 °C
• Appearance: /
• Density: 1.66 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.654
• Storage Temp.: 2-8°C(protect from light)
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 14.13±0.10(Predicted)
• CAS DataBase Reference: (2-AMINO-5-BROMOPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-5-BROMOPHENYL)METHANOL(20712-12-3)
• EPA Substance Registry System: (2-AMINO-5-BROMOPHENYL)METHANOL(20712-12-3)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 20712-12-3(Hazardous Substances Data)

Usage

General Description

(2-Amino-5-bromophenyl)methanol is a chemical compound with the molecular formula C7H8BrNO. It is a white to off-white crystalline solid that is used as an intermediate in the production of pharmaceuticals and organic compounds. (2-AMINO-5-BROMOPHENYL)METHANOL is a derivative of phenol with a bromine atom and an amino group attached to the benzene ring. It is commonly used in organic synthesis and chemical research, and its properties and reactivity make it a valuable building block in the synthesis of various pharmaceuticals and bioactive compounds. However, it is important to handle this compound with care, as it may be toxic if ingested or inhaled, and it can cause irritation to the skin and eyes upon contact.

InChI:InChI=1/C7H8BrNO/c8-6-1-2-7(9)5(3-6)4-10/h1-3,10H,4,9H2

Upstream product

• 5344-90-1 2-Aminobenzyl alcohol 
• 52727-57-8 5-bromo-2-aminobenzoic acid methyl ester 
• 20357-20-4 5-bromo-2-nitrobenzaldehyde 
• 1241894-37-0 5-bromo-2-nitrobenzylic alcohol 
• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 13292-87-0 dimethyl sulfide borane 
• 20244-61-5 2,4,4,6-Tetrabromo-2,5-cyclohexadien-1-one 

Downstream Products

• 443360-99-4 N-(4-bromo-2-hydroxymethyl-phenyl)-acrylamide 
• 886756-66-7 N-[4-bromo-2-(hydroxymethyl)phenyl]-2-chloroacetamide 
• 886756-21-4 {5-bromo-2-[(chloroacetyl)amino]phenyl}methyl chloroacetate 
• 1021692-84-1 C₁₄H₁₂Br₂O₂Se 
• 1017783-09-3 6-bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one 
• 3894-25-5 6-bromo-2-phenyl-quinoline 
• 1439384-18-5 N-(4-bromo-2-formylphenyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Relevant articles and documents

Zn(OTf)2-catalyzed reactions of ethenetricarboxylates with 2-aminobenzaldehydes leading to tetrahydroquinoline derivatives

(Graph Presented) Quinolines are an important class of compounds, and the development of new efficient synthetic strategies for the construction of quinolines is of considerable interest. Zinc triflate catalyzed cyclization of ethenetricarboxylate derivat

Construction of a benzo[b]azepine skeleton through decarboxylative ylide [6+1] annulations with modified vinyl benzoxazinanones

A Lewis acid-promoted [6+1] annulation between sulfur ylides and modified vinyl benzoxazinanones was described. In this reaction, the newly designed vinyl benzoxazinanones could serve as a novel six-atom synthon, and the key to success is the installation of an electron-withdrawing group on the alkene moiety of the benzoxazinanones. A broad range of substrates are compatible with this mild reaction system, thereby providing a facile and practical approach for constructing a benzo[b]azepine skeleton.

Preparation and Application of α-Imino Ketones through One-Pot Tandem Reactions Based on Heyns Rearrangement

α-Imino ketone is a useful building block for the preparation of α-amino ketones and α-amino alcohols. However, its preparation has been seldomly seen. Herein, a metal-free and operationally simple strategy has been developed to generate α-imino ketones with high regioselectivity. Meanwhile, the method allowed for the preparation of various N,O-ketals with high regioselectivities and diastereoselectivities through cascade reactions in one pot.