1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane

Base Information

• Chemical Name: 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane
• CAS No.: 220220-06-4
• Molecular Formula: C₁₆H₁₈N₄O₂
• Molecular Weight: 298.345

Synonyms:1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane

Chemical Property of 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane

There total 2 articles about 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

4-Fluoronitrobenzene (350-46-9,178603-76-4) + 1-(pyridin-4-yl)-1,4-diazepane (194853-82-2) → 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane (220220-06-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 13h;

DOI:10.1016/j.bmc.2004.02.022

Reference yield:

1-(4-nitrophenyl)hexahydro-1H-1,4-diazepine dihydrochloride + di-tert-butyl dicarbonate (24424-99-5) + 4-chlorpyridine hydrochloride (7379-35-3) → 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane (220220-06-4)

Guidance literature:

With sodium hydrogencarbonate; triethylamine; In 1,4-dioxane; i-Amyl alcohol; chloroform;

Reference yield:

1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane (220220-06-4) → 4-(4-pyridin-4-yl-[1,4]diazepan-1-yl)-phenylamine

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 16h;

DOI:10.1016/j.bmc.2004.02.022

upstream raw materials:

4-Fluoronitrobenzene

1-(pyridin-4-yl)-1,4-diazepane

di-tert-butyl dicarbonate

4-chlorpyridine hydrochloride

Downstream raw materials:

7-[({4-[4-(pyridin-4-yl)-1,4-diazepan-1-yl]phenyl}amino)methyl]-2-naphthonitrile

ethyl ({[(7-cyano-2-naphthyl)methyl]{4-[4-(pyridin-4-yl)-1,4-diazepan-1-yl]phenyl}amino}sulfonyl)acetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220220-06-4 1-(4-nitrophenyl)-4-(pyridin-4-yl)-1,4-diazepane

Send

Send

Metric Ton KG G Pound L ML

Send

Send