2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester

Base Information

• Chemical Name: 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester
• CAS No.: 130655-36-6
• Molecular Formula: C₁₈H₂₅NO₄
• Molecular Weight: 319.401
• Mol file: 130655-36-6.mol

Synonyms:2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester

Chemical Property of 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester

There total 1 articles about 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-ethoxycarbonyl-1-cyclopentanone (611-10-9) + 2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester (130655-36-6)

Guidance literature:

In ethanol; at 100 ℃; for 1.33333h;

DOI:10.1248/cpb.38.1462

Reference yield:

oxalyl dichloride (79-37-8) + 2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester (130655-36-6) → 1-[2-(3,4-Dimethoxy-phenyl)-ethyl]-2,3-dioxo-2,3,4,5-tetrahydro-1H-cyclopenta[b]pyrrole-3a-carboxylic acid ethyl ester

Guidance literature:

In benzene; at 0 ℃; for 1.5h;

DOI:10.1248/cpb.38.1462

Reference yield:

2-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-cyclopent-1-enecarboxylic acid ethyl ester (130655-36-6) → C33H42N2O6

Guidance literature:

Multi-step reaction with 3 steps

1: chloroform / 20 °C

2: chloroform-d1 / 20 °C

3: Imidazole hydrochloride / chloroform-d1; chloroform / 48 h / 20 °C

With Imidazole hydrochloride; In chloroform-d1; chloroform;

DOI:10.1021/jo301061r

upstream raw materials:

2-ethoxycarbonyl-1-cyclopentanone

2-(3,4-dimethoxyphenyl)-ethylamine