2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide

Base Information

• Chemical Name: 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide
• CAS No.: 917462-03-4
• Molecular Formula: C₁₃H₁₁FN₄O
• Molecular Weight: 258.255
• Mol file: 917462-03-4.mol

Synonyms:2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide

Chemical Property of 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide

There total 2 articles about 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2-aminoisonicotinic acid hydrazide (58481-01-9) + 4-fluorobenzaldehyde (459-57-4) → 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide (917462-03-4)

Guidance literature:

In 1,4-dioxane; for 3h; Heating;

Reference yield:

methyl 2-aminoisonicotinate (6937-03-7) → 2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide (917462-03-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / hydrazine hydrate / methanol / 3 h / Heating

2: 68 percent / dioxane / 3 h / Heating

With hydrazine hydrate; In 1,4-dioxane; methanol;

Reference yield: 54.0%

2-aminoisonicotinic acid (4-fluorobenzylidine) hydrazide (917462-03-4) + p-acetylaminobenzenesulfonyl chloride (121-60-8) → 2-[N1-(4-acetylsulfanilamido)]-4-(4-fluorobenzylidene)pyridinecarbohydrazide

Guidance literature:

With pyridine; In acetone; at 20 ℃;

upstream raw materials:

2-aminoisonicotinic acid hydrazide

4-fluorobenzaldehyde

methyl 2-aminoisonicotinate