(2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol

Base Information

• Chemical Name: (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol
• CAS No.: 657357-41-0
• Molecular Formula: C₄₀H₅₂O₃S₂Si₂
• Molecular Weight: 701.154

Synonyms:(2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol

Chemical Property of (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol

There total 3 articles about (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1.3-propanedithiol (109-80-8) + tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxytetrahydrofuran-2-yl)methoxy)diphenylsilane (148903-86-0) → (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol (657357-41-0)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at -10 ℃;

DOI:10.1002/anie.200352102

Reference yield:

D-2-deoxyribose (452-51-7,13046-70-3,29780-54-9,36792-87-7,36792-88-8,113890-35-0,113890-38-3) → (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol (657357-41-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Me₂SiCl₂

2: imidazole

3: 89 percent / BF₃*Et₂O / CH₂Cl₂ / -10 °C

With 1H-imidazole; boron trifluoride diethyl etherate; dimethylsilicon dichloride; In dichloromethane;

DOI:10.1002/anie.200352102

Reference yield:

1-O-methyl-2-deoxy-D-ribofuranoside (51255-17-5,51255-18-6,60134-26-1,89577-26-4,96038-80-1,96039-31-5,144301-84-8,144301-85-9) → (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol (657357-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1: imidazole

2: 89 percent / BF₃*Et₂O / CH₂Cl₂ / -10 °C

With 1H-imidazole; boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1002/anie.200352102

upstream raw materials:

1.3-propanedithiol

tert-butyl(((2R,3S)-3-((tert-butyldiphenylsilyl)oxy)-5-methoxytetrahydrofuran-2-yl)methoxy)diphenylsilane

D-2-deoxyribose

1-O-methyl-2-deoxy-D-ribofuranoside

Downstream raw materials:

1,3-bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-one

(2R,3S,5S)-2,5-Bis-(4,5-dimethoxy-2-nitro-benzyloxy)-2-hydroxymethyl-tetrahydro-furan-3-ol

(2S,3S,5R)-2,5-Bis-(4,5-dimethoxy-2-nitro-benzyloxy)-2-hydroxymethyl-tetrahydro-furan-3-ol

C₄₁H₆₈N₂O₁₆Si₃

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 657357-41-0 (2R,3S)-1,3-Bis-(tert-butyl-diphenyl-silanyloxy)-4-[1,3]dithian-2-yl-butan-2-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send