N-formyl-3,4-dihydroxyphenylalanine methyl ester

Base Information

• Chemical Name: N-formyl-3,4-dihydroxyphenylalanine methyl ester
• CAS No.: 57085-16-2
• Molecular Formula: C₁₁H₁₃NO₅
• Molecular Weight: 239.228
• Mol file: 57085-16-2.mol

Synonyms:N-formyl-3,4-dihydroxyphenylalanine methyl ester

Chemical Property of N-formyl-3,4-dihydroxyphenylalanine methyl ester

Chemical Property:

Purity/Quality:

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Technology Process of N-formyl-3,4-dihydroxyphenylalanine methyl ester

There total 1 articles about N-formyl-3,4-dihydroxyphenylalanine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

sodium formate (141-53-7) + L-dopa methyl ester hydrochloride (1421-65-4) → N-formyl-3,4-dihydroxyphenylalanine methyl ester (57085-16-2)

Guidance literature:

With formic acid; acetic anhydride; at 20 ℃; for 3h;

Reference yield: 83.0%

N-formyl-3,4-dihydroxyphenylalanine methyl ester (57085-16-2) → N-formyl-3,4-dihydroxy-6-nitrophenylalanine methyl ester (261961-43-7)

Guidance literature:

With sulfuric acid; sodium nitrite; at 20 ℃; for 2h;

Reference yield: 48.0%

2-Methoxyethoxymethyl chloride (3970-21-6) + N-formyl-3,4-dihydroxyphenylalanine methyl ester (57085-16-2) → N-formyl(3-O'-methoxyethoxymethyl)-3,4-dihydroxyphenylalanine methyl ester

Guidance literature:

With sodium carbonate; at 20 ℃; for 3h;

upstream raw materials:

sodium formate

L-dopa methyl ester hydrochloride

Downstream raw materials:

N-formyl-3,4-dihydroxy-6-nitrophenylalanine methyl ester