α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside

Base Information

• Chemical Name: α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside
• CAS No.: 22224-42-6
• Molecular Formula: C₂₈H₂₄O₉
• Molecular Weight: 504.493
• Mol file: 22224-42-6.mol

Synonyms:α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside

Chemical Property of α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside

There total 9 articles about α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

acetyl chloride (75-36-5) + 1,3,5-tri-O-benzoyl-α-D-ribofuranoside (22224-41-5) → α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside (22224-42-6)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 20 ℃; for 10h;

DOI:10.1021/jo0003652

Reference yield:

acetic anhydride (108-24-7) + 1,3,5-tri-O-benzoyl-α-D-ribofuranoside (22224-41-5) → α-D-2-O-acetyl-1,3,5-tri-O-benzoylribofuranoside (22224-42-6)

Guidance literature:

With pyridine;

DOI:10.1021/ja01599a048

Reference yield:

D-Arabinose (10323-20-3) → O2-Acetyl-O1,O3,O5-tribenzoyl-β-D-arabinofuranose (22224-42-6,104320-81-2,115404-07-4)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogen chloride; pyridine

2: hydrogen bromide; acetic acid

3: aqueous acetone

4: pyridine

With pyridine; hydrogenchloride; hydrogen bromide; acetic acid; acetone;

DOI:10.1021/ja01541a058

upstream raw materials:

acetic anhydride

O¹,O³,O⁵-Tribenzoyl-β-D-arabinofuranose

D-Arabinose

methyl tri-O-benzoyl-α-D-arabinofuranoside

Downstream raw materials:

1,2-di-O-acetyl-3,5-di-O-benzoyl-β-D-ribofuranoside

1-(2-O-acetyl-3,5-di-O-benzoyl-β-D-ribofuranosyl)adenine

1-(2-O-acetyl-5-O-benzoyl-3-deoxy-β-D-erythro-pentofuranosyl)-4-methoxy-2-pyrimidone

3'-deoxycytidine