4-BROMO-N-ETHYLBENZENESULPHONAMIDE

Base Information

• Chemical Name: 4-BROMO-N-ETHYLBENZENESULPHONAMIDE
• CAS No.: 1984-25-4
• Molecular Formula: C8H10BrNO2S
• Molecular Weight: 264.143
• Hs Code.: 2935009090
• Mol file: 1984-25-4.mol

Synonyms:Benzenesulfonamide,p-bromo-N-ethyl- (6CI,7CI,8CI);4-(N-Ethylsulfamoyl)phenyl bromide;4-Bromo-N-ethylbenzenesulfonamide;N-Ethyl-4-bromobenzenesulfonamide;N-Ethyl-p-bromobenzenesulfonamide;NSC 406251;

Chemical Property of 4-BROMO-N-ETHYLBENZENESULPHONAMIDE

Chemical Property:

• Vapor Pressure: 7.48E-05mmHg at 25°C
• Melting Point: 69-71 °C
• Refractive Index: 1.564
• Boiling Point: 342.5 °C at 760 mmHg
• PKA: 11.29±0.50(Predicted)
• Flash Point: 161 °C
• PSA: 54.55000
• Density: 1.529 g/cm³
• LogP: 3.21900
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

N-Ethyl4-bromobenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMO-N-ETHYLBENZENESULPHONAMIDE

There total 3 articles about 4-BROMO-N-ETHYLBENZENESULPHONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethanamine hydrochloride (557-66-4) + 4-bromobenzenesulfonyl chloride (98-58-8) → 4-bromo-N-ethylbenzenesulfonamide (1984-25-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

ethylamine (75-04-7,85404-22-4) → 4-bromo-N-ethylbenzenesulfonamide (1984-25-4)

Guidance literature:

With alkali;

Reference yield:

→ 4-bromo-N-ethylbenzenesulfonamide (1984-25-4)

Guidance literature:

upstream raw materials:

ethylamine

ethanamine hydrochloride

4-bromobenzenesulfonyl chloride

Downstream raw materials:

4-(N-ethylsulfamoyl)phenylboronic acid

benzyl 4-(4-(ethylsulfamoyl)phenyl)-3-(1-propyn-1-yl)-1-piperazinecarboxylate

4-(2S)-(4-((6-amino-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-N-ethylbenzenesulfonamide

4-(2R)-(4-((6-amino-3-pyridinyl)sulfonyl)-2-(1-propyn-1-yl)-1-piperazinyl)-N-ethylbenzenesulfonamide

Refernces

• 1、 -. "PROTEIN KINASE MKK4 INHIBITORS FOR PROMOTING LIVER REGENERATION OR REDUCING OR PREVENTING HEPATOCYTE DEATH". Page/Page column 75. . Retrieved 2019/08/26.
• 2、 Dong, Xiang,Sang, Rui,Wang, Qiang,Tang, Xiang-Ying,Shi, Min. "Copper-catalyzed trifluoromethylation and cyclization of aromatic-sulfonyl-group-tethered alkenes for the construction of 1,2-benzothiazinane dioxide type compounds". supporting information. p. 16910 - 16915. Retrieved 2014/01/06.