[2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester

Base Information

• Chemical Name: [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester
• CAS No.: 35335-17-2
• Molecular Formula: C₁₆H₂₆Br₂O₆P₂
• Molecular Weight: 536.134
• Mol file: 35335-17-2.mol

Synonyms:[2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester

Chemical Property of [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester

There total 4 articles about [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,4-bis(bromomethyl)-2,5-dibromobenzene (35335-16-1) + triethyl phosphite (122-52-1) → [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester (35335-17-2)

Guidance literature:

at 90 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c0ob00156b

Reference yield:

2,5-dibromo-p-xylene (1074-24-4) → [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester (35335-17-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NBS

With N-Bromosuccinimide;

DOI:10.1016/0040-4020(72)80133-9

Reference yield:

para-xylene (106-42-3) → [2,5-dibromo-4-(diethoxyphosphorylmethyl)-benzyl]phosphonic acid diethyl ester (35335-17-2)

Guidance literature:

Multi-step reaction with 3 steps

1: bromine; iodine / dichloromethane / 18 h / 12 °C

2: N-Bromosuccinimide / tetrachloromethane / 8 h / Reflux

3: 6 h / Reflux

With N-Bromosuccinimide; bromine; iodine; In tetrachloromethane; dichloromethane;

DOI:10.1016/j.molstruc.2013.07.031

upstream raw materials:

1,4-bis(bromomethyl)-2,5-dibromobenzene

triethyl phosphite

2,5-dibromo-p-xylene

para-xylene

Downstream raw materials:

(E,E)-2,5-dibromo-1,4-bis-[2-(3',4'-bis-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenyl)-vinyl]-benzene

C₅₈H₉₀Br₂N₂O₁₆

1,4-dibromo-2,5-bis(4-tert-butylstyryl)benzene

C₅₈H₄₄N₂