Technology Process of trans,trans-2,5-distyryl-1,4-dibromobenzene
There total 6 articles about trans,trans-2,5-distyryl-1,4-dibromobenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
benzyl bromide;
With
triphenylphosphine;
In
toluene;
for 5h;
Reflux;
With
potassium tert-butylate;
In
tetrahydrofuran;
at 0 ℃;
for 0.5h;
Inert atmosphere;
2,5-dibromoterephthalaldehyde;
In
tetrahydrofuran;
at 20 ℃;
for 12h;
Overall yield = 80 %; Overall yield = 8.7 g;
Inert atmosphere;
DOI:10.1002/anie.201403509
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: iodine; bromine / dichloromethane / 17 h / 20 °C / Darkness; Cooling with ice
2.1: bromine / tetrachloromethane / 4 h / Irradiation; Reflux
3.1: silver nitrate / acetonitrile; water / 5 h / Reflux; Inert atmosphere
4.1: triphenylphosphine / toluene / 5 h / Reflux
4.2: 0.5 h / 0 °C / Inert atmosphere
4.3: 12 h / 20 °C / Inert atmosphere
With
bromine; iodine; silver nitrate; triphenylphosphine;
In
tetrachloromethane; dichloromethane; water; toluene; acetonitrile;
DOI:10.1002/anie.201403509
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: bromine / tetrachloromethane / 4 h / Irradiation; Reflux
2.1: silver nitrate / acetonitrile; water / 5 h / Reflux; Inert atmosphere
3.1: triphenylphosphine / toluene / 5 h / Reflux
3.2: 0.5 h / 0 °C / Inert atmosphere
3.3: 12 h / 20 °C / Inert atmosphere
With
bromine; silver nitrate; triphenylphosphine;
In
tetrachloromethane; water; toluene; acetonitrile;
DOI:10.1002/anie.201403509
