3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione

Base Information

• Chemical Name: 3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione
• CAS No.: 81572-13-6
• Molecular Formula: C₁₅H₂₀N₂O₄
• Molecular Weight: 292.335
• Mol file: 81572-13-6.mol

Synonyms:3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione

Chemical Property of 3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione

There total 1 articles about 3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dimethoxyphenethyl bromide (40173-90-8) + 5,5-dimethyl-imidazolidine-2,4-dione (77-71-4) → 3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione (81572-13-6)

Guidance literature:

With potassium hydroxide; Yield given. Multistep reaction; 1.) Me₂SO, 100-110 deg C, 1 h, 2a.) RT, 2 d, 2b.) 70 deg C, 5 h;

DOI:10.1021/jo00135a022

Reference yield: 81.0%

3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione (81572-13-6) → 3-(3',4'-dimethoxyphenethyl)-4-hydroxy-5,5-dimethyl-2-imidazolidinone (81572-17-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 48h; Ambient temperature;

DOI:10.1021/jo00135a022

Reference yield:

3-(3',4'-dimethoxyphenethyl)-5,5-dimethyl-2,4-imidazolidinedione (81572-13-6) → 8,9-Dimethoxy-1,1-dimethyl-1,5,6,10b-tetrahydro-2H-imidazo[5,1-a]isoquinolin-3-one (81583-49-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / LiAlH₄ / tetrahydrofuran / 48 h / Ambient temperature

2: 72 percent / trifluoroacetic anhydride, trifluoroacetic acid / CH₂Cl₂ / 48 h / Heating

With lithium aluminium tetrahydride; trifluoroacetic acid; trifluoroacetic anhydride; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo00135a022

upstream raw materials:

3,4-dimethoxyphenethyl bromide

5,5-dimethyl-imidazolidine-2,4-dione

Downstream raw materials:

3-(3',4'-dimethoxyphenethyl)-4-hydroxy-5,5-dimethyl-2-imidazolidinone

8,9-Dimethoxy-1,1-dimethyl-1,5,6,10b-tetrahydro-2H-imidazo[5,1-a]isoquinolin-3-one