2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

Base Information

Chemical Name:2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid
CAS No.:104394-35-6
Molecular Formula:C₂₅H₂₆O₃
Molecular Weight:374.48
Hs Code.:

Synonyms:2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

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Chemical Property of 2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

Chemical Property:

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Technology Process of 2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

There total 4 articles about 2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 104421-44-5
2,2-dimethyl-3-(p-methoxyphenyl)-4-hydroxy-4,4-diphenylbutanoic acid lactone

: 104394-35-6
2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

Guidance literature:: With ammonia; lithium; In tetrahydrofuran; for 2h; Heating;
DOI:10.1021/jo00374a022

Reference yield:

: 104394-32-3
2,2-diphenyl-2-(p-methoxyphenyl)ethanol

: 104394-35-6
2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / pyridinium chlorochromate / CH₂Cl₂ / 2 h

2: 59 percent / zinc / benzene / 36 h / Heating

3: 97 percent / ammonia, lithium / tetrahydrofuran / 2 h / Heating

With ammonia; lithium; pyridinium chlorochromate; zinc; In tetrahydrofuran; dichloromethane; benzene;
DOI:10.1021/jo00374a022

Reference yield:

: 104394-34-5
2,2-diphenyl-2-(p-methoxyphenyl)acetaldehyde

: 104394-35-6
2,2-dimethyl-3-(p-methoxyphenyl)-4,4-diphenylbutanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / zinc / benzene / 36 h / Heating

2: 97 percent / ammonia, lithium / tetrahydrofuran / 2 h / Heating

With ammonia; lithium; zinc; In tetrahydrofuran; benzene;
DOI:10.1021/jo00374a022