Technology Process of 3-(4-methoxybenzoyl)hex-5-en-1-yl acetate
There total 3 articles about 3-(4-methoxybenzoyl)hex-5-en-1-yl acetate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(4-methoxyphenyl)but-3-yn-1-yl acetate; allyl alcohol;
With
silver tetrafluoroborate; [1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-(3H)-ylidene]gold(I)chloride;
In
tetrahydrofuran;
at 65 ℃;
for 15h;
Inert atmosphere;
In
tetrahydrofuran;
at 120 ℃;
for 6h;
diastereoselective reaction;
Sealed tube;
DOI:10.1039/c2cc37166a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: dmap; pyridine / 2 h / Cooling with ice
2.1: [1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-(3H)-ylidene]gold(I)chloride; silver tetrafluoroborate / tetrahydrofuran / 15 h / 65 °C / Inert atmosphere
2.2: 6 h / 120 °C / Sealed tube
With
pyridine; dmap; silver tetrafluoroborate; [1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-(3H)-ylidene]gold(I)chloride;
In
tetrahydrofuran;
2.2: |Claisen Rearrangement;
DOI:10.1039/c2cc37166a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / neat (no solvent) / 1 h / 40 °C / Inert atmosphere
2.1: dmap; pyridine / 2 h / Cooling with ice
3.1: [1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-(3H)-ylidene]gold(I)chloride; silver tetrafluoroborate / tetrahydrofuran / 15 h / 65 °C / Inert atmosphere
3.2: 6 h / 120 °C / Sealed tube
With
pyridine; dmap; silver tetrafluoroborate; [1,3-bis(2,6-diisopropylphenyl)-1H-imidazol-2-(3H)-ylidene]gold(I)chloride; sodium hydride;
In
tetrahydrofuran;
3.2: |Claisen Rearrangement;
DOI:10.1039/c2cc37166a