Dexivacaine

Base Information

Chemical Name:Dexivacaine
CAS No.:24358-84-7
Molecular Formula:C₁₅H₂₂N₂O
Molecular Weight:246.352
Hs Code.:
UNII:QI846AL4NC
DSSTox Substance ID:DTXSID30179091
Nikkaji Number:J16.719C
Wikidata:Q27287277
NCI Thesaurus Code:C65371
ChEMBL ID:CHEMBL2104634
Mol file:24358-84-7.mol

Synonyms:dexivacain

Suppliers and Price of Dexivacaine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DEXIVACAINE 95.00%
5MG
$ 504.14

Total 7 raw suppliers

Chemical Property of Dexivacaine

Chemical Property:

Vapor Pressure:4.52E-06mmHg at 25°C
Melting Point:148-150 °C
Boiling Point:383.1°Cat760mmHg
PKA:14.85±0.70(Predicted)
Flash Point:185.5°C
PSA：35.83000
Density:1.077g/cm³
LogP:3.31360
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:246.173213330
Heavy Atom Count:18
Complexity:282

Purity/Quality:

99% ^*data from raw suppliers

DEXIVACAINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2C
Isomeric SMILES:CC1=C(C(=CC=C1)C)NC(=O)[C@@H]2CCCCN2C
Uses Anesthetic. (S)-Mepavacaine is a chemical often used as a local anesthetic.

Technology Process of Dexivacaine

There total 17 articles about Dexivacaine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 39627-98-0
2-pyridine-carboxamide-N-(2,6-dimethylphenyl)

: 96-88-8,22801-44-1,24358-84-7,34811-66-0
mepivacaine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; acetic acid; In methanol; water; at 50 ℃;
DOI:10.1002/ejoc.201700824

Reference yield: 53.0%

: 626-67-5
N-methylcyclohexylamine

: 40397-98-6
2,5-dimethylphenyl isocyanate

: N-(2,6-dimethylphenyl)-1-(2-(2,6-dimethylphenylamino)-2-oxoethyl)piperidine-2-carboxamide

: N²,N⁶-bis(2,6-dimethylphenyl)-1-methylpiperidine-2,6-dicarboxamide

: 96-88-8,22801-44-1,24358-84-7,34811-66-0
mepivacaine

: 13327-12-3
N-(2,6-dimethylphenyl)-2-(piperidin-1-yl)acetamide

Guidance literature:: With triethyl borane; oxygen; at 20 ℃; for 37h; Further byproducts.;
DOI:10.1021/ol7023295

Reference yield:

: 67-56-1
methanol

: 39627-98-0
2-pyridine-carboxamide-N-(2,6-dimethylphenyl)

: 15883-20-2,27262-40-4,27262-43-7,78341-12-5
2',6'-pipecoloxylidide

: 96-88-8,22801-44-1,24358-84-7,34811-66-0
mepivacaine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; acetic acid; at 70 ℃; under 37503.8 Torr; Temperature;
DOI:10.1002/ejoc.201700824