Technology Process of C24H20FN3O4
There total 9 articles about C24H20FN3O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen; palladium(II) hydroxide;
In
tetrahydrofuran; methanol;
for 1.5h;
under 2585.81 Torr;
Overall yield = 86 %; Overall yield = 745 mg;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: iron; ammonium acetate / toluene; water / 105 °C
2.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere
2.2: Inert atmosphere
3.1: trichlorophosphate / 10 h / Reflux
4.1: potassium carbonate; sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 100 °C / Inert atmosphere
5.1: triethylamine / dichloromethane; toluene / 1.5 h / -78 - 20 °C
6.1: hydrogen; palladium(II) hydroxide / methanol; tetrahydrofuran / 1.5 h / 2585.81 Torr
With
ammonium acetate; hydrogen; sodium methylate; palladium(II) hydroxide; iron; sodium hydride; potassium carbonate; triethylamine; trichlorophosphate;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium methylate / 1,2-dimethoxyethane / 0.5 h / Inert atmosphere
1.2: Inert atmosphere
2.1: trichlorophosphate / 10 h / Reflux
3.1: potassium carbonate; sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 100 °C / Inert atmosphere
4.1: triethylamine / dichloromethane; toluene / 1.5 h / -78 - 20 °C
5.1: hydrogen; palladium(II) hydroxide / methanol; tetrahydrofuran / 1.5 h / 2585.81 Torr
With
hydrogen; sodium methylate; palladium(II) hydroxide; sodium hydride; potassium carbonate; triethylamine; trichlorophosphate;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;