S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

Base Information

Chemical Name:S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate
CAS No.:865423-59-2
Molecular Formula:C₂₁H₁₆N₂O₃S
Molecular Weight:376.436
Hs Code.:

Synonyms:S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

Chemical Property:

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Technology Process of S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

There total 4 articles about S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 93073-37-1
5-(4-methoxybenzyl)-4-amino-1,3,4-oxadiazole-2-thiol

: 879-18-5
naphthalene-1-carbonic acid chloride

: 865423-59-2
S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

Guidance literature:: 5-(4-methoxybenzyl)-4-amino-1,3,4-oxadiazole-2-thiol; With potassium hydroxide; In ethanol; water; for 1h; Reflux;

naphthalene-1-carbonic acid chloride; In ethanol; water; for 6h; Reflux;

Reference yield:

: 23786-14-3
4-methoxy-phenyl acetic acid methyl ester

: 865423-59-2
S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine hydrate

2: potassium hydroxide

3: potassium hydroxide

With hydrazine hydrate; potassium hydroxide;
DOI:10.3390/molecules16021297

Reference yield:

: 57676-49-0
2-(4-methoxyphenyl)acetic acid hydrazide

: 865423-59-2
S-(5-(4-methoxybenzyl)-1,3,4-oxadiazole-2-yl) naphthalene-1-carbothioate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide

2: potassium hydroxide

With potassium hydroxide;
DOI:10.3390/molecules16021297