C₁₀H₉ClO₂

Base Information

• Chemical Name: C₁₀H₉ClO₂
• CAS No.: 1429641-12-2
• Molecular Formula: C₁₀H₉ClO₂
• Molecular Weight: 196.633
• Mol file: 1429641-12-2.mol

Synonyms:C₁₀H₉ClO₂

Chemical Property of C₁₀H₉ClO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₉ClO₂

There total 6 articles about C₁₀H₉ClO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-methoxy-phenyl)-acrylic acid (51747-42-3) → C10H9ClO2 (1429641-12-2)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere;

Reference yield:

4-methoxy-phenyl acetic acid methyl ester (23786-14-3) → C10H9ClO2 (1429641-12-2)

Guidance literature:

Multi-step reaction with 3 steps

1: tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate / toluene / 12 h / 80 °C / Inert atmosphere

2: potassium hydroxide / tetrahydrofuran; water / 12 h / 70 °C / Inert atmosphere

3: oxalyl dichloride; N,N-dimethyl-formamide

With oxalyl dichloride; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; N,N-dimethyl-formamide; potassium hydroxide; In tetrahydrofuran; water; toluene;

DOI:10.1002/anie.201106927

Reference yield:

methyl 2-(4-methoxyphenyl)prop-2-enoate (50415-68-4) → C10H9ClO2 (1429641-12-2)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / tetrahydrofuran; water / 12 h / 70 °C / Inert atmosphere

2: oxalyl dichloride; N,N-dimethyl-formamide

With oxalyl dichloride; N,N-dimethyl-formamide; potassium hydroxide; In tetrahydrofuran; water;

DOI:10.1002/anie.201106927

upstream raw materials:

2-(4-methoxy-phenyl)-acrylic acid

4-methoxy-phenyl acetic acid methyl ester

methyl 2-(4-methoxyphenyl)prop-2-enoate

Methyltriphenylphosphonium bromide

Downstream raw materials:

2-(4-methoxyphenyl)acrylamide

methyl (S)-2-(4-methyoxyphenyl)propionate

(S)-(+)-2-(4'-methoxyphenyl)propanoic acid

2-(4-methoxy-phenyl)-acrylic acid