Technology Process of 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester]
There total 1 articles about 5-thiazolecarboxylic methyl ester 4-N-[(2,4-dimethyl-phenyl)-phosphonamidate methyl ester] which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2,4-dimethyl-phenyl)-phosphonic acid methyl ester;
With
oxalyl dichloride;
N,N-dimethyl-formamide;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
methyl 4-amino-1,3-thiazole-5-carboxylatte;
With
sodium hydride;
In
tetrahydrofuran;
at 0 - 20 ℃;