(2-Aminoethyl)guanidine dihydrochloride

Base Information

• Chemical Name: (2-Aminoethyl)guanidine dihydrochloride
• CAS No.: 68027-22-5
• Molecular Formula: C3H12Cl2N4
• Molecular Weight: 175.06018
• European Community (EC) Number: 268-206-5
• DSSTox Substance ID: DTXSID20987460
• Mol file: 68027-22-5.mol

Synonyms:(2-Aminoethyl)guanidine dihydrochloride;68027-22-5;N-(2-aminoethyl)guanidine dihydrochloride;(2-Aminoethyl)guanidine HCl;1-(2-aminoethyl)guanidine dihydrochloride;2-(2-aminoethyl)guanidine;dihydrochloride;EINECS 268-206-5;C3H12Cl2N4;C3H10N4.2ClH;SCHEMBL2129107;C3-H10-N4.2Cl-H;DTXSID20987460;KYJBBNCBVZZHOA-UHFFFAOYSA-N;2-aminoethylguanidine dihydrochloride;AKOS030757484;N-(2-aminoethyl)guanidinedihydrochloride;EN300-246804;N-(2-Aminoethyl)guanidine--hydrogen chloride (1/2);Z2235813444

Chemical Property of (2-Aminoethyl)guanidine dihydrochloride

Chemical Property:

• Vapor Pressure: 0.0145mmHg at 25°C
• Boiling Point: 257.4°C at 760 mmHg
• Flash Point: 109.5°C
• PSA: 87.92000
• LogP: 1.92340
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 174.0439018
• Heavy Atom Count: 9
• Complexity: 63.3

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CN=C(N)N)N.Cl.Cl

Technology Process of (2-Aminoethyl)guanidine dihydrochloride

There total 8 articles about (2-Aminoethyl)guanidine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-(tert-butyloxycarbonyl)-1,2-ethanediamine hydrochloride (79513-35-2,117083-06-4) + 1H-pyrazole-1-carboximidamide hydrochloride (4023-02-3) → 2-amino-ethylguanidine dihydrochloride (68027-22-5,94291-67-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 60 ℃; for 2h;

DOI:10.1021/acsinfecdis.0c00068

Reference yield: 86.0%

N-(1-aminoethan-2-yl)-2-amino-4,6-dimethoxypyrimidine → 2-amino-ethylguanidine dihydrochloride (68027-22-5,94291-67-5)

Guidance literature:

With hydrogenchloride; In water; at 80 ℃; for 12h; Sealed tube; Green chemistry;

DOI:10.1016/j.tetlet.2015.07.007

Reference yield: 74.0%

→ 2-amino-ethylguanidine dihydrochloride (68027-22-5,94291-67-5)

Guidance literature:

upstream raw materials:

N-<2-<(tert-butoxycarbonyl)amino>ethyl>guanidine

N-BOC-2-aminoethylguanidine hydroiodide

N-(tert-butyloxycarbonyl)-1,2-ethanediamine hydrochloride

1H-pyrazole-1-carboximidamide hydrochloride