cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

Base Information

Chemical Name:cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate
CAS No.:1185570-76-6
Molecular Formula:C₂₉H₃₁F₂N₃O₄
Molecular Weight:523.58
Hs Code.:

Synonyms:cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

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Chemical Property of cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

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Technology Process of cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

There total 7 articles about cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: cyclopentyl 2-amino-2-methylpropanoate hydrochloride

: 1151805-31-0
{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]-phenyl}acetaldehyde

: 1185570-76-6
cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

Guidance literature:: With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 20 ℃; for 16h;

Reference yield:

: 602312-20-9
6-amino-5-(2,4-difluorobenzoyl)-1-[4-(2-hydroxyethyl)phenyl]-pyridin-2(1H)-one

: 1185570-76-6
cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

Guidance literature:: Multi-step reaction with 2 steps

1: Dess-Martin periodane / dichloromethane / 0 - 20 °C

2: sodium tris(acetoxy)borohydride / tetrahydrofuran / 16 h / 20 °C

With sodium tris(acetoxy)borohydride; Dess-Martin periodane; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1185571-45-2
cyclopentyl N-(tert-butoxycarbonyl)-2-methylalaninate

: 1185570-76-6
cyclopentyl N-(2-{4-[6-amino-5-(2,4-difluorobenzoyl)-2-oxopyridin-1(2H)-yl]phenyl}ethyl)-2-methylalaninate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 24 h / 20 °C

2: sodium tris(acetoxy)borohydride / tetrahydrofuran / 16 h / 20 °C

With hydrogenchloride; sodium tris(acetoxy)borohydride; In tetrahydrofuran; 1,4-dioxane;