N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Base Information

Chemical Name:N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide
CAS No.:1262859-61-9
Molecular Formula:C₁₅H₁₄BrFN₂O₅S
Molecular Weight:433.255
Hs Code.:

Synonyms:N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Suppliers and Price of N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Chemical Property:

Purity/Quality:

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Technology Process of N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

There total 8 articles about N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1262859-60-8
(S)-1-amino-2-(5-bromo-2-fluoro-phenyl)-propan-2-ol

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 1262859-61-9
N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; water; at 0 - 5 ℃; for 0.5h;

Reference yield:

: 1262859-57-3
(S)-2-(5-bromo-2-fluoro-phenyl)-2-methyl-oxirane

: 1262859-61-9
N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium chloride; sodium azide / ethanol

2: NaOH; LiAlH₄ / water; tetrahydrofuran

3: sodium hydroxide / tetrahydrofuran

With sodium hydroxide; NaOH; sodium azide; LiAlH₄; ammonium chloride; In tetrahydrofuran; ethanol; water;

Reference yield:

: 460-00-4
1-Bromo-4-fluorobenzene

: 1262859-61-9
N-[(S)-2-(5-Bromo-2-fluoro-phenyl)-2-hydroxy-propyl]-2-nitro-benzenesulfonamide

Guidance literature:: Multi-step reaction with 7 steps

1: n-butyllithium / hexane; tetrahydrofuran; acetone

2: phosphoric acid / dichloromethane; hexane

3: potassium carbonate; K₃Fe(CN)6; Na₂S₂O₅ / K₂OsO₂(OH)4 / t-BuOH-H₂O

4: hydrogenchloride; sodium hydroxide / dichloromethane

5: ammonium chloride; sodium azide / ethanol

6: NaOH; LiAlH₄ / water; tetrahydrofuran

7: sodium hydroxide / tetrahydrofuran

With hydrogenchloride; sodium hydroxide; NaOH; n-butyllithium; sodium azide; LiAlH₄; K₃Fe(CN)6; Na₂S₂O₅; phosphoric acid; ammonium chloride; potassium carbonate; K₂OsO₂(OH)4; In tetrahydrofuran; ethanol; hexane; dichloromethane; t-BuOH-H₂O; water; acetone;