3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

Base Information

• Chemical Name: 3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL
• CAS No.: 80284-15-7
• Molecular Formula: C11H16O3
• Molecular Weight: 196.242
• Mol file: 80284-15-7.mol

Synonyms:3-tert-Butyl-4,5-dihydroxyanisole;3-tert-Butyl-5-methoxy-1,2-benzenediol;NSC 607535;

Chemical Property of 3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

Chemical Property:

• Vapor Pressure: 0.000105mmHg at 25°C
• Refractive Index: 1.534
• Boiling Point: 327.5 °C at 760 mmHg
• Flash Point: 151.9 °C
• PSA: 49.69000
• Density: 1.108 g/cm³
• LogP: 2.40390
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

3-TERT-BUTYL-5-METHOXYCATECHOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL

There total 7 articles about 3-T-BUTYL-5-METHOXY-1,2-BENZENEDIOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-Acetoxy-4-methoxy-6-t-butylphenol (1947-12-2) → 3-tert-butyl-5-methoxy-pyrocatechol (80284-15-7)

Guidance literature:

With hydrogenchloride; In methanol; at 90 ℃; for 0.75h;

DOI:10.1039/c39910000104

Reference yield: 69.0%

methanol (67-56-1) + 3,5-di-tert-butyl-1,2-benzoquinone (34105-76-5) → 3-tert-butyl-5-methoxy-pyrocatechol (80284-15-7) + 3,6-Di-tert-butyl-4-methoxy-benzene-1,2-diol (62783-44-2)

Guidance literature:

With hydrogenchloride;

DOI:10.1007/BF00949485

Reference yield:

3-tert-Butyl-4-hydroxyanisole (121-00-6,1341-82-8) → 3-tert-butyl-5-methoxy-pyrocatechol (80284-15-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Fremy's salt, KH₂PO₄ / H₂O; acetone

2: sidium hydrosulfite / aq. ethanol

With potassium dihydrogenphosphate; potassiuim nitrosodisulfonate; sodium hydrogensulfite; In ethanol; water; acetone;

DOI:10.1002/jps.2600770507

upstream raw materials:

2,3,5-triacetoxy-tert-butylbenzene

methanol

3,5-di-tert-butyl-1,2-benzoquinone

3-tert-butyl-5-methoxy-1,2-benzoquinone

Downstream raw materials:

3-tert-butyl-5-methoxy-1,2-benzoquinone

4,5-diacetoxy-3-tert-butylanisole

Refernces

• 1、 Takizawa, Yasuomi,Tateishi, Akira,Sugiyama, Junichi,Yoshida, Hiroyuki,Yoshihara, Nobutoshi. "The ortho-Acetoxylation of Phenols by Copper(II) Acetate". . p. 104 - 105. Retrieved 2007/10/02.
• 2、 Novikova, I. A.,Vol'eva, V. B.,Komissarova, N. L.,Belostotskaya, I. S.,Ershov, V. V.. "REACTION OF 3,6-DI-tert-BUTYL-o-BENZOQUINONE WITH ACIDS". . p. 1732 - 1735. Retrieved 2007/10/02.