Technology Process of C37H41Cl3N2O19
There total 18 articles about C37H41Cl3N2O19 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C37H40Cl3NO20;
With
4-methyl-morpholine; isobutyl chloroformate;
In
tetrahydrofuran;
at -30 ℃;
for 0.5h;
Inert atmosphere;
With
ammonia;
In
tetrahydrofuran; methanol;
at 0 ℃;
for 0.5h;
DOI:10.1021/ja4000933
- Guidance literature:
-
C37H40Cl3NO20;
With
4-methyl-morpholine; isobutyl chloroformate;
In
tetrahydrofuran;
at -30 ℃;
for 0.5h;
Inert atmosphere;
With
ammonia;
In
tetrahydrofuran; methanol;
at 0 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 2,6-di-tert-butyl-pyridine; 1,2-dimethoxy-4-(2-propenyl)benzene; trifluoromethylsulfonic anhydride / dichloromethane / 1.5 h / -78 °C / Inert atmosphere; Molecular sieve
2.1: triethylsilane; trifluorormethanesulfonic acid / dichloromethane / 2.5 h / -78 °C / Molecular sieve; Inert atmosphere
3.1: pyridine; dmap / dichloromethane / 3 h / 20 °C / Inert atmosphere
4.1: hydrogen; palladium 10% on activated carbon; trichloroacetic acid / methanol / 0.25 h
5.1: [bis(acetoxy)iodo]benzene; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / water; dichloromethane / 1.5 h / 20 °C
6.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / -30 °C / Inert atmosphere
6.2: 0.5 h / 0 °C
With
4-methyl-morpholine; pyridine; triethylsilane; dmap; 2,6-di-tert-butyl-pyridine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; trifluorormethanesulfonic acid; trifluoromethylsulfonic anhydride; [bis(acetoxy)iodo]benzene; 1,2-dimethoxy-4-(2-propenyl)benzene; palladium 10% on activated carbon; hydrogen; isobutyl chloroformate; trichloroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/ja4000933
