1426099-68-4

Upstream product

• 3150-20-7 4-methoxyphenyl β-D-galactopyranoside 
• 150-76-5 4-methoxy-phenol 
• 2872-65-3 4-methoxyphenyl 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside 
• 25878-60-8 D-galactose pentaacetate 
• 1885-14-9 phenyl chloroformate 
• 176299-96-0 4-methoxyphenyl 4,6-O-benzylidene-β-D-galactopyranoside 

Downstream Products

• 1138125-17-3 C₄₂H₄₆Cl₃NO₁₈ 
• 1138125-22-0 C₄₃H₄₅Cl₃F₃NO₂₀S 
• 1138124-43-2 C₄₄H₄₈Cl₃NO₁₉ 
• 1426099-69-5 C₃₁H₃₈Cl₃N₃O₁₈ 
• 1138124-35-2 C₄₄H₄₈Cl₃NO₁₉ 
• 1426099-71-9 C₃₇H₄₂Cl₃NO₁₉ 
• 1426099-72-0 C₃₇H₄₀Cl₃NO₂₀ 
• 1426099-74-2 C₃₇H₄₁Cl₃N₂O₁₉ 
• 1138123-83-7 C₄₂H₄₄Cl₃NO₁₈ 

Relevant academic research and scientific papers

Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors

New antibiotic drugs need to be identified to address rapidly developing resistance of bacterial pathogens to common antibiotics. The natural antibiotic moenomycin A is the prototype for compounds that bind to bacterial peptidoglycan glycosyltransferases

CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS

The present invention provides methods of synthesizing moenomycin analogs of Formula (I). The present invention also provides compositions comprising a compound of Formula (I) and kits for synthesizing compounds of Formula (I).

METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS

The present invention provides moenomycin-based probe compounds of Formula (I) for use in screening inhibitors of bacterial glycosyltransferases. The present invention also provides bacterial glycosyltransferase screening assays using compounds of Formula (I).