ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Base Information

Chemical Name:ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate
CAS No.:638215-15-3
Molecular Formula:C₂₅H₂₄F₃NO₅
Molecular Weight:475.464
Hs Code.:

Synonyms:ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Suppliers and Price of ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

There total 5 articles about ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 638215-14-2
ethyl ({4-[(2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

: 638215-15-3
ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 18h;

Reference yield:

: 403612-14-6
(4-hydroxy-2-methylphenoxy)acetic acid ethyl ester

: 638215-15-3
ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 24.5 h / 0 - 20 °C

2: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 21 h / 45 °C

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 20 °C

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; sodium carbonate; triphenylphosphine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dimethoxyethane; water; 1: Mitsunobu reaction / 2: Suzuki Coupling;

Reference yield:

: 638215-11-9
1-(6-bromo-2-pyridinyl)-2-{[(1,1-dimethylethyl)(dimethyl)silyl]oxy}ethanol

: 638215-15-3
ethyl ({4-[(2-hydroxy-1-{6-[4-(trifluoromethyl)phenyl]-2-pyridinyl}ethyl)oxy]-2-methylphenyl}oxy)acetate

Guidance literature:: Multi-step reaction with 3 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 24.5 h / 0 - 20 °C

2: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,2-dimethoxyethane; water / 21 h / 45 °C

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 18 h / 20 °C

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; sodium carbonate; triphenylphosphine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dimethoxyethane; water; 1: Mitsunobu reaction / 2: Suzuki Coupling;