2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester
CAS No.:627511-95-9
Molecular Formula:C₅₂H₆₂O₈
Molecular Weight:815.059
Hs Code.:

Synonyms:2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Suppliers and Price of 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

There total 5 articles about 2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 627511-83-5
2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-9-hydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

: 627511-95-9
2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Guidance literature:: With hydrogen fluoride; In acetonitrile; at 40 ℃;
DOI:10.1016/j.tetlet.2003.08.082

Reference yield:

: 209340-30-7
(S)-2-((S)-2-Benzyloxy-4-trityloxy-butyl)-oxirane

: 627511-95-9
2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / n-BuLi; HMPA / tetrahydrofuran / -20 °C

2: DIBALH / CH₂Cl₂; hexane / 20 °C

3: Et₃N / CH₂Cl₂ / 20 °C

4: Hg(ClO₄)2; CaCO₃ / tetrahydrofuran; H₂O / 0 °C

5: 89 percent / aq. HF / acetonitrile / 40 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; mercury(II) perchlorate; hydrogen fluoride; diisobutylaluminium hydride; triethylamine; calcium carbonate; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
DOI:10.1016/j.tetlet.2003.08.082

Reference yield:

: tert-Butyl-[(S)-1-[1,3]dithian-2-ylmethyl-1-methyl-2-((R)-2-phenyl-[1,3]dioxan-4-yl)-ethoxy]-dimethyl-silane

: 627511-95-9
2,2-Dimethyl-propionic acid (3S,5S,9S,11S)-3,11-bis-benzyloxy-5,9-dihydroxy-5-methyl-7-oxo-13-trityloxy-tridecyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 85 percent / n-BuLi; HMPA / tetrahydrofuran / -20 °C

2: DIBALH / CH₂Cl₂; hexane / 20 °C

3: Et₃N / CH₂Cl₂ / 20 °C

4: Hg(ClO₄)2; CaCO₃ / tetrahydrofuran; H₂O / 0 °C

5: 89 percent / aq. HF / acetonitrile / 40 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; mercury(II) perchlorate; hydrogen fluoride; diisobutylaluminium hydride; triethylamine; calcium carbonate; In tetrahydrofuran; hexane; dichloromethane; water; acetonitrile;
DOI:10.1016/j.tetlet.2003.08.082