methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate

Base Information

• Chemical Name: methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate
• CAS No.: 1621378-10-6
• Molecular Formula: C₂₂H₁₅F₃IN₃O₅
• Molecular Weight: 585.278

Synonyms:methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate

Chemical Property of methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate

There total 5 articles about methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1-(4-iodophenyl)-1-(2-nitro-4-(trifluoromethyl)phenyl)hydrazine (1621378-08-2) + 4-Methoxycarbonylbenzoyl chloride (7377-26-6) → methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate (1621378-10-6)

Guidance literature:

With triethylamine; In dichloromethane; at -5 - 20 ℃; Inert atmosphere;

DOI:10.1021/jo500898e

Reference yield:

1-fluoro-2-nitro-4-trifluoromethyl-benzene (367-86-2) → methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate (1621378-10-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / water; dimethyl sulfoxide / 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride / pyridine / 20 h / 80 °C / Inert atmosphere

3: triethylamine / dichloromethane / -5 - 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; potassium carbonate; triethylamine; In pyridine; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/jo500898e

Reference yield:

1-benzylidene-2-(4-iodophenyl)hydrazine (65447-26-9) → methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate (1621378-10-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / water; dimethyl sulfoxide / 20 °C / Inert atmosphere

2: hydroxylamine hydrochloride / pyridine / 20 h / 80 °C / Inert atmosphere

3: triethylamine / dichloromethane / -5 - 20 °C / Inert atmosphere

With hydroxylamine hydrochloride; potassium carbonate; triethylamine; In pyridine; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/jo500898e

upstream raw materials:

1-fluoro-2-nitro-4-trifluoromethyl-benzene

1-benzylidene-2-(4-iodophenyl)hydrazine

1-(4-iodophenyl)-1-(2-nitro-4-(trifluoromethyl)phenyl)hydrazine

4-Methoxycarbonylbenzoyl chloride

Downstream raw materials:

C₂₂H₁₅F₃IN₃O₂

6-(trifluoromethyl)-1-(4-iodophenyl)-3-(4-(methoxycarbonyl)phenyl)-1,2-dihydrobenzo[1,2,4]triazin-2-yl

6-(trifluoromethyl)-1-(4-iodophenyl)-3-(4-(hydroxycarbonyl)phenyl)-1,2-dihydrobenzo[1,2,4]triazin-2-yl

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1621378-10-6 methyl 4-(2-(4-(benzyloxy)phenyl)-2-(2-nitro-4-(trifluoromethyl)-phenyl)hydrazinecarbonyl)benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send