N,N'-Diacetylcystine

Base Information Edit

Chemical Name:N,N'-Diacetylcystine
CAS No.:5545-17-5
Molecular Formula:C10H16N2O6S2
Molecular Weight:324.379
Hs Code.:29225090
NSC Number:203782,203780
DSSTox Substance ID:DTXSID20970791
Nikkaji Number:J2.244.904D
Mol file:5545-17-5.mol

Synonyms:(Ac-Cys-OH);DiNAC;NSC203780;Cystine, N,N'-diacetyl-, L-;2-acetamido-3-[(2-acetamido-2-carboxyethyl)disulfanyl]propanoic acid;(2R)-2-acetamido-3-[[(2R)-2-acetamido-2-carboxyethyl]disulfanyl]propanoic acid;NSC-203780;NSC203782;L-Cystine,N'-diacetyl-;Cystine, N,N'-diacetyl-;Cystine,N'-diacetyl-, L-;SCHEMBL2140974;DTXSID20970791;N,N'-Bis(1-hydroxyethylidene)cystine;NSC-203782;FT-0629434;EN300-717889;2-acetamido-3-[(2-acetamido-3-hydroxy-3-oxo-propyl)disulfanyl]propanoic acid;3-[(2-CARBOXY-2-ACETAMIDOETHYL)DISULFANYL]-2-ACETAMIDOPROPANOIC ACID;2765062-75-5

Suppliers and Price of N,N'-Diacetylcystine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N,N’-Diacetyl-L-cystine,90%
25g
$ 900.00

TRC
N,N’-Diacetyl-L-cystine,90%
5g
$ 205.00

Sigma-Aldrich
Acetylcysteine impurity C European Pharmacopoeia (EP) Reference Standard
a0152000
$ 190.00

Crysdot
N,N'-Diacetyl-L-Cystine 95+%
5g
$ 450.00

Crysdot
N,N'-Diacetyl-L-Cystine 95+%
1g
$ 150.00

Chem-Impex
(Ac-L-Cys-OH)2(Disulfidebond),≥99.5%(Chiralpurity) ≥99.5%(Chiralpurity)
1G
$ 128.13

Chem-Impex
(Ac-L-Cys-OH)2(Disulfidebond),99.5%(Chiralpurity) 99.5%(Chiralpurity)
250MG
$ 67.20

Chem-Impex
(Ac-L-Cys-OH)2(Disulfidebond),≥99.5%(Chiralpurity) ≥99.5%(Chiralpurity)
5G
$ 576.58

Cayman Chemical
N,N'-Diacetyl-L-cystine ≥90%
5g
$ 266.00

Cayman Chemical
N,N'-Diacetyl-L-cystine ≥90%
10g
$ 472.00

Total 29 raw suppliers

Chemical Property of N,N'-Diacetylcystine Edit

Chemical Property:

Appearance/Colour:White Powder
Vapor Pressure:2.13E-22mmHg at 25°C
Melting Point:55-72 °C
Refractive Index:1.582
Boiling Point:715.5 °C at 760 mmHg
Flash Point:386.5 °C
PSA：183.40000
Density:1.451 g/cm³
LogP:0.32820
Storage Temp.:-15°C
Solubility.:Methanol (Slightly), Water (Slightly)
XLogP3:-0.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:324.04497858
Heavy Atom Count:20
Complexity:354

Purity/Quality:

99%, ^*data from raw suppliers

N,N’-Diacetyl-L-cystine,90% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(CSSCC(C(=O)O)NC(=O)C)C(=O)O
Uses A treatment for dermal imflammations caused by leukotriene production. Contains N-acetyl cysteine. (AC-CYS-OH)2 is a disulfide dimer of N-acetylcysteine with immunomodulatory properties. Its intact disulfide bridge has been shown to be important for its ability to modify contact sensitivity/delayed hypersensitivity reactions in mice. At 3 μM/kg/day, DiNAC also demonstrates anti-atherosclerotic effects, improving endothelial function in Watanabe heritable hyperlipidemic rabbits. N,N’-Diacetyl-L-cystine (DiNAC) is a disulfide dimer of N-acetylcysteine with immunomodulatory properties. Its intact disulfide bridge has been shown to be important for its ability to modify contact sensitivity/delayed hypersensitivity reactions in mice.1,2 At 3 μM/kg/day, DiNAC also demonstrates anti-atherosclerotic effects, improving endothelial function in Watanabe heritable hyperlipidemic rabbits. Acetylcysteine EP Impurity C.

Technology Process of N,N'-Diacetylcystine

There total 31 articles about N,N'-Diacetylcystine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 616-91-1,7696-05-1
N-acetylcystein

: 5545-17-5
N,N'-diacetyl-L-cystine

Guidance literature:: With bis(4-methoxyphenyl)telluride; 5,15,10,20-tetraphenylporphyrin; In dichloromethane; isopropyl alcohol; at 0 ℃; for 0.25h; Irradiation;
DOI:10.1021/jo200496r