C₂₃H₂₅N₅O₅S

Base Information

• Chemical Name: C₂₃H₂₅N₅O₅S
• CAS No.: 1346245-10-0
• Molecular Formula: C₂₃H₂₅N₅O₅S
• Molecular Weight: 483.548
• Mol file: 1346245-10-0.mol

Synonyms:C₂₃H₂₅N₅O₅S

Chemical Property of C₂₃H₂₅N₅O₅S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₂₅N₅O₅S

There total 12 articles about C₂₃H₂₅N₅O₅S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C22H23N5O3 (1346242-78-1) + methanesulfonyl chloride (124-63-0) → C23H25N5O5S (1346245-10-0)

Guidance literature:

With triethylamine; In dichloromethane; at 5 - 20 ℃; for 2h; Inert atmosphere;

Reference yield:

7‐bromo‐2‐(1‐methyl‐1H‐pyrazol‐4‐yl)quinoxaline (1083325-87-4) → C23H25N5O5S (1346245-10-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

2.2: 5 - 20 °C / Inert atmosphere

3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

3.2: Cooling with ice

4.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; sodium hydride; triethylamine; sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

7-bromo-2-chloroquinoxaline (89891-65-6) → C23H25N5O5S (1346245-10-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium carbonate / triphenylphosphine; palladium diacetate / 1,2-dimethoxyethane; water / 4 h / Reflux

2.1: sodium t-butanolate / palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / 1,4-dioxane / 90 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 1 h / 5 °C / Inert atmosphere

3.2: 5 - 20 °C / Inert atmosphere

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 20 °C

4.2: Cooling with ice

5.1: triethylamine / dichloromethane / 2 h / 5 - 20 °C / Inert atmosphere

With tetrabutyl ammonium fluoride; sodium hydride; sodium carbonate; triethylamine; sodium t-butanolate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane; water; N,N-dimethyl-formamide; mineral oil;

upstream raw materials:

3.5-dimethoxyaniline

C₂₂H₂₃N₅O₃

methanesulfonyl chloride

7-bromo-1H-quinoxalin-2-one

Downstream raw materials:

C₂₉H₃₆N₆O₂

C₂₉H₃₄N₆O₄

C₂₆H₂₆N₆O₂

C₂₃H₂₆N₆O₂