C₂₈H₂₀Cl₄N₆O₂

Base Information

• Chemical Name: C₂₈H₂₀Cl₄N₆O₂
• CAS No.: 1428946-36-4
• Molecular Formula: C₂₈H₂₀Cl₄N₆O₂
• Molecular Weight: 614.318
• Mol file: 1428946-36-4.mol

Synonyms:C₂₈H₂₀Cl₄N₆O₂

Chemical Property of C₂₈H₂₀Cl₄N₆O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₂₀Cl₄N₆O₂

There total 7 articles about C₂₈H₂₀Cl₄N₆O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + 5'-tert-butyl-(1,1':3',1-terphenyl)-3,3-diol (1428946-28-4) → C28H20Cl4N6O2 (1428946-36-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tet.2013.03.035

Reference yield:

4-tert-Butylaniline (769-92-6) → C28H20Cl4N6O2 (1428946-36-4)

Guidance literature:

Multi-step reaction with 5 steps

1: bromine; acetic acid / 5 h / 85 °C / Inert atmosphere

2: sulfuric acid; sodium nitrite / ethanol / 13.75 h / 50 - 80 °C / Inert atmosphere

3: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; toluene / 30 h / Inert atmosphere; Reflux

4: boron tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere

5: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; bromine; boron tribromide; sodium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine; sodium nitrite; In tetrahydrofuran; ethanol; dichloromethane; toluene;

DOI:10.1016/j.tet.2013.03.035

Reference yield:

2,6-dibromo-4-(tert-butyl)aniline (10546-67-5) → C28H20Cl4N6O2 (1428946-36-4)

Guidance literature:

Multi-step reaction with 4 steps

1: sulfuric acid; sodium nitrite / ethanol / 13.75 h / 50 - 80 °C / Inert atmosphere

2: sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / ethanol; toluene / 30 h / Inert atmosphere; Reflux

3: boron tribromide / dichloromethane / 0 - 20 °C / Inert atmosphere

4: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; boron tribromide; sodium carbonate; N-ethyl-N,N-diisopropylamine; sodium nitrite; In tetrahydrofuran; ethanol; dichloromethane; toluene;

DOI:10.1016/j.tet.2013.03.035

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

5'-tert-butyl-(1,1':3',1-terphenyl)-3,3-diol

4-tert-Butylaniline

2,6-dibromo-4-(tert-butyl)aniline