N-(2-chlorophenyl)-N-ethylethenesulfonamide

Base Information

• Chemical Name: N-(2-chlorophenyl)-N-ethylethenesulfonamide
• CAS No.: 1404508-90-2
• Molecular Formula: C₁₀H₁₂ClNO₂S
• Molecular Weight: 245.73
• Mol file: 1404508-90-2.mol

Synonyms:N-(2-chlorophenyl)-N-ethylethenesulfonamide

Chemical Property of N-(2-chlorophenyl)-N-ethylethenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-chlorophenyl)-N-ethylethenesulfonamide

There total 3 articles about N-(2-chlorophenyl)-N-ethylethenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

2-Chloroethanesulfonyl chloride (1622-32-8) + o-chloro-N-ethylaniline (13519-74-9) → N-(2-chlorophenyl)-N-ethylethenesulfonamide (1404508-90-2)

Guidance literature:

With sodium hydroxide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c2ob26531a

Reference yield:

o-chloroaniline (95-51-2) → N-(2-chlorophenyl)-N-ethylethenesulfonamide (1404508-90-2)

Guidance literature:

Multi-step reaction with 3 steps

1: dmap / dichloromethane / 0 - 20 °C / Inert atmosphere

2: borane-THF / tetrahydrofuran / 4 h / 65 °C / Inert atmosphere

3: sodium hydroxide / dichloromethane / 0 - 20 °C / Inert atmosphere

With dmap; borane-THF; sodium hydroxide; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c2ob26531a

Reference yield:

N-(2-chlorophenyl)acetamide (533-17-5) → N-(2-chlorophenyl)-N-ethylethenesulfonamide (1404508-90-2)

Guidance literature:

Multi-step reaction with 2 steps

1: borane-THF / tetrahydrofuran / 4 h / 65 °C / Inert atmosphere

2: sodium hydroxide / dichloromethane / 0 - 20 °C / Inert atmosphere

With borane-THF; sodium hydroxide; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c2ob26531a

upstream raw materials:

N-(2-chlorophenyl)acetamide

2-Chloroethanesulfonyl chloride

o-chloro-N-ethylaniline

o-chloroaniline