1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide

Base Information

• Chemical Name: 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide
• CAS No.: 1220170-01-3
• Molecular Formula: C₁₉H₁₇FN₆O
• Molecular Weight: 364.382
• Mol file: 1220170-01-3.mol

Synonyms:1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide

Chemical Property of 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide

There total 1 articles about 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-[1-(toluene-4-sulfonyl)-1H-pyrazol-3-yl]-propylamine (1220166-27-7) + 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid (1220165-92-3) → 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide (1220170-01-3)

Guidance literature:

1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

(S)-1-[1-(toluene-4-sulfonyl)-1H-pyrazol-3-yl]-propylamine; In N,N-dimethyl-formamide; for 3h;

Reference yield:

1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide (1220170-01-3) + methanesulfonyl chloride (124-63-0) → 1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1-(1-methanesulfonyl-1H-pyrazol-3-yl)-propyl]-amide (1220170-03-5)

Guidance literature:

1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1(1H-pyrazol-3-yl)-propyl]-amide; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.333333h;

methanesulfonyl chloride; In tetrahydrofuran; mineral oil; for 3h;

upstream raw materials:

(S)-1-[1-(toluene-4-sulfonyl)-1H-pyrazol-3-yl]-propylamine

1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid

Downstream raw materials:

1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid [(S)-1-(1-methanesulfonyl-1H-pyrazol-3-yl)-propyl]-amide