Technology Process of 3,4-dimethoxy-5-fluorophenethylamine
There total 9 articles about 3,4-dimethoxy-5-fluorophenethylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; zinc;
In
methanol;
at 0 ℃;
for 0.5h;
chemoselective reaction;
DOI:10.1055/s-0034-1379481
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium acetate / acetic acid / 1 h / 90 - 100 °C / Molecular sieve
2: hydrogenchloride; zinc / methanol / 0.5 h / 0 °C
With
hydrogenchloride; ammonium acetate; zinc;
In
methanol; acetic acid;
1: |Henry Nitro Aldol Condensation;
DOI:10.1055/s-0034-1379481
- Guidance literature:
-
Multi-step reaction with 6 steps
1: ethanol / 2 h / Reflux
2: chloroform / 20 °C
3: acetic acid; hexamethylenetetramine; hydrogenchloride / water / Reflux
4: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane / 12 h / 20 °C
5: ammonium acetate / acetic acid / 1 h / 90 - 100 °C / Molecular sieve
6: hydrogenchloride; zinc / methanol / 0.5 h / 0 °C
With
hydrogenchloride; hexamethylenetetramine; ammonium acetate; tetra(n-butyl)ammonium hydrogensulfate; acetic acid; sodium hydroxide; zinc;
In
methanol; ethanol; dichloromethane; chloroform; water; acetic acid;
5: |Henry Nitro Aldol Condensation;
DOI:10.1055/s-0034-1379481
