2-(4-methylphenyl)-quinazoline

Base Information

• Chemical Name: 2-(4-methylphenyl)-quinazoline
• CAS No.: 1208259-15-7
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.274
• Mol file: 1208259-15-7.mol

Synonyms:2-(4-methylphenyl)-quinazoline

Chemical Property of 2-(4-methylphenyl)-quinazoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenyl)-quinazoline

There total 18 articles about 2-(4-methylphenyl)-quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-methylphenyl aldehyde (529-20-4) + 2-amino-1-benzylamine (4403-69-4) → 2-(4-methylphenyl)-quinazoline (1208259-15-7)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; water; at 100 ℃; for 12h;

DOI:10.1039/c9sc04060a

Reference yield: 98.0%

→ 2-(4-methylphenyl)-quinazoline (1208259-15-7)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; at 100 ℃; for 12h; Sealed tube;

Reference yield: 90.0%

o-methylphenylacetic acid (644-36-0) + 2-Nitrobenzyl alcohol (612-25-9) → 2-(4-methylphenyl)-quinazoline (1208259-15-7)

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; sulfur; urea; In dimethyl sulfoxide; at 140 ℃; for 2h;

DOI:10.1055/s-0040-1707113

upstream raw materials:

2-iodobenzaldehyde

2-methylbenzimidamide hydrochloride

2-methylphenyl aldehyde

2-amino-1-benzylamine

Downstream raw materials:

(E)-4-styryl-2-(o-tolyl)quinazoline